Please join us for the next of its series KHP DEO Research Webinar featuring our new RD Lawrence Chair for Diabetic Medicine, Prof Victoria Salem.
Prof Victoria Salem “Engineered pancreatic tissue: from disease modelling to regenerative medicine for diabetes”
We are entering a new dawn of Regenerative Medicine for Type 1 Diabetes, with clinical trials under way of stem cell derived beta cells (King’s a major recruitment site in the UK). Early results are extremely encouraging, with reports of patients achieving over two years of insulin independence. However there still remain many barriers to widespread adoption of this type of treatment as a functional cure for T1D. This includes the need to circumvent systemic immunosuppression and to find alternative transplant sites that are more accessible and more hospitable to long term graft survival and function.
Prof Victoria Salem will talk about the role of biomaterials in those endeavours, with a particular focus on some projects in her lab that are looking to understand how islet vascularisation can be augmented for transplant success. This relates to the development of vascularised islet on chip platforms which have utility for the screening of biomaterials for translational use, as well as improved readouts of basic islet function in vitro.
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